Brainstem neuroimaging of nociception and pain circuitries
نویسندگان
چکیده
منابع مشابه
Capsaicin, Nociception and Pain.
Capsaicin, the pungent ingredient of the hot chili pepper, is known to act on the transient receptor potential cation channel vanilloid subfamily member 1 (TRPV1). TRPV1 is involved in somatic and visceral peripheral inflammation, in the modulation of nociceptive inputs to spinal cord and brain stem centers, as well as the integration of diverse painful stimuli. In this review, we first describ...
متن کاملNociception and Pain in Animals
Recent evidence has shown that fi sh display aversive behavioral and physiological reactions and a suspension of normal behavior in response to noxious stimuli that cause pain in other animals and humans. In addition to these behavioral responses, scientists have identifi ed a peripheral nociceptive system and recorded specifi c changes in the brain activity of fi sh during noxious stimulation....
متن کاملProstanoids in nociception and pain.
Prostaglandins are lipid mediators produced by cyclooxygenases from arachidonic acid, which serve pivotal functions in inflammation and pain. Inhibition of their production is the major analgesic mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)-but also the source of most of their unwanted effects. While the development of selective inhibitors of inducible cyclooxygenase (C...
متن کاملSupraspinal modulation of trigeminal nociception and pain.
OBJECTIVE This study examined modulation of trigeminal pain/nociception by 2 supraspinal mechanisms: emotional controls of nociception and diffuse noxious inhibitory controls. BACKGROUND Prior research suggests emotional picture viewing (emotional controls) and tonic noxious stimuli (diffuse noxious inhibitory controls) engage supraspinal mechanisms to modulate pain and nociceptive processes....
متن کاملDifferent Brain Circuitries Mediating Controllable and Uncontrollable Pain.
UNLABELLED Uncontrollable, compared with controllable, painful stimulation can lead to increased pain perception and activation in pain-processing brain regions, but it is currently unknown which brain areas mediate this effect. When pain is controllable, the lateral prefrontal cortex (PFC) seems to inhibit pain processing, although it is unclear how this is achieved. Using fMRI in healthy volu...
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ژورنال
عنوان ژورنال: PAIN Reports
سال: 2019
ISSN: 2471-2531
DOI: 10.1097/pr9.0000000000000745